Seaberry CardioMed Studies

1. Cardiovascular disease 

Chai Qiuyan et al. 1989. The experimental studies on the cardiovascular pharmacology of seabuckthorn extract from Hippophae rhamnoides L. Proceedings of the International Symposium on Seabuckthorn, Xi'an, China. 392-397

Cheng TJ, Wang YB, Gao LP, Sun YF, Zhang J. 2003. The protection of seed oil of Hippophae rharmnoides on ischemic cerebral infarction in rats.:Zhongguo Zhong Yao Za Zhi. 28(6):548-50.

Inhibitory effects of total flavones of Hippophae Rhamnoides L on thrombosis in mouse femoral artery and in vitro platelet aggregation.:Life Sci. 2003 Apr 4;72(20):2263-71.

Zhang X, Zhang M, Gao Z, Wang J, Wang Z. 2001. Effect of total flavones of Hippophae rhamnoides L. on sympathetic activity in hypertension.:Hua Xi Yi Ke Da Xue Xue Bao. 32(4):547-50.

Rui Livin et a. 1989. Effects of seabuckthorn oil on lipid peroxidation of guinea pigs

erythrocyte membranes. Proceedings of International Symposium on Seabuckthorn, Xi'an, China, 358-364.

Ju Haisong et al. 1989. Scavenging effects of total flavonoids of Hippophae on active

oxygen radicals. Proceedings of International Symposium on Seabuckthorn, Xi'an, China, 365-367.

 Yang XY, Qu WJ, Xu ZL, Miu-Qian , Zhu LX, Xu ZM. 2006. Effect of flavonoids from Hippophae rhamniodes residues on blood lipoid metabolism and antioxidative activity in climacteric rats.:Zhongguo Zhong Yao Za Zhi. 31(13):1109-12.  

Suomela JP, Ahotupa M, Yang B, Vasankari T, Kallio H. 2006. Absorption of flavonols derived from sea buckthorn (Hippophae rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans.:J Agric Food Chem. 20;54(19):7364-9.

Shukla SK, Chaudhary P, Kumar IP, Samanta N, Afrin F, Gupta ML, Sharma UK, Sinha AK, Sharma YK, Sharma RK. 2006. Protection from radiation-induced mitochondrial and genomic DNA damage by an extract of Hippophae rhamnoides.:Environ Mol Mutagen. 47(9):647-56.  

Bao M, Lou Y. 2006. Flavonoids from seabuckthorn protect endothelial cells (EA.hy926) from oxidized low-density lipoprotein induced injuries via regulation of LOX-1 and eNOS expression.:J Cardiovasc Pharmacol. 48(1):834-41.

Gupta R, Flora SJ. 2006. Protective effects of fruit extracts of Hippophae rhamnoides L. against arsenic toxicity in Swiss albino mice.:Hum Exp Toxicol. 25(6):285-95.

Liu CL, Liu HQ, Deng YH, Liu ML. 2006. Study on the purification and scavenging free radical activity of water soluble polysaccharide of leave in Hippohae rhamnoides L.:Zhong Yao Cai. 29(2):151-4.  

Goel HC, Gupta D, Gupta S, Garg AP, Bala M. 2005. Protection of mitochondrial system by Hippophae rhamnoides L. against radiation-induced oxidative damage in mice.:J Pharm Pharmacol. 57(1):135-43.

Wu D, Meng Z. 2003. Effect of sulfur dioxide inhalation on the glutathione redox system in mice and protective role of sea buckthorn seed oil.:Arch Environ Contam Toxicol. 45(3):423-8.

Ruan A, Min H, Meng Z, L¨¹ Z. 2003. Protective effects of seabuckthorn seed oil on mouse injury induced by sulfur dioxide inhalation.:Inhal Toxicol. 15(10):1053-8.

Geetha S, Sai Ram M, Mongia SS, Singh V, Ilavazhagan G, Sawhney RC. Evaluation of antioxidant activity of leaf extract of Seabuckthorn (Hippophae rhamnoides L.) on chromium(VI) induced oxidative stress in albino rats.:

Suleyman H, Gumustekin K, Taysi S, Keles S, Oztasan N, Aktas O, Altinkaynak K, Timur H, Akcay F, Akar S, Dane S, Gul M. 2002. Beneficial effects of Hippophae rhamnoides L. on nicotine induced oxidative stress in rat blood compared with vitamin E.:Biol Pharm Bull. 25(9):1133-6.

 

2. Anti-Inflammation

Yang B, et al. 2006. Secoisolariciresinol and matairesinol of sea buckthorn (Hippophaë rhamnoides L.) berries of different subspecies and harvesting times. J Agric Food Chem. 54(21):8065-70.  

L. D. Lebedeva et al. 1989 Screening investigation of the anti-inflammation activity of

seabuckthorn oil. Proceedings of International Symposium on Seabuckthorn, Xi'an, China, 398.

Wu Airu et al. 1992. Observation of the applied clinical effects on treating the chronic

cervicitis with seabuckthorn embolus. Seabuckthorn 5 (2) : 22-25.

Che xiping et al. 1992. Experimantal research on the effects of seabuckthorn oil embolus on eliminating inflammation and easing pain. Seabuckthorn 5 (2) : 26-29.

Zhang Wenlu et al. 1988. Preliminry results of the experimental observation and the clinical application of treating the acute radio-dermatitis with seabuckthorn. Seabuckthorn 1 (1) : 27-30.

Larmo P, Alin J, Salminen E, Kallio H, Tahvonen R. 2007. Effects of sea buckthorn berries on infections and inflammation: a double-blind, randomized, placebo-controlled trial. Eur J Clin Nutr.

Padwad Y, Ganju L, Jain M, Chanda S, Karan D, Kumar Banerjee P, Chand Sawhney R. 2005. Effect of leaf extract of Seabuckthorn on lipopolysaccharide induced inflammatory response in murine macrophages.:Int Immunopharmacol. 6(1):46-52.   

Ganju L, Padwad Y, Singh R, Karan D, Chanda S, Chopra MK, Bhatnagar P, Kashyap R, Sawhney RC. 2005. Anti-inflammatory activity of Seabuckthorn (Hippophae rhamnoides) leaves.:Int Immunopharmacol. 5(12):1675-84. 26.

Hepatoprotective effect of the sea buckthorn-and-pinks oil.:Lik Sprava. 2000 Sep;(6):96-9. Ukrainian.Lipkan GM, Oli?nyk OA.

 

3. Diabetes

Cao Q, Qu W, Deng Y, Zhang Z, Niu W, Pan Y. 2003. Effect of flavonoids from the seed and fruit residue of Hippophae rhamnoides L. on glycometabolism in mice.:Zhong Yao Cai. 26(10):735-7.

Eccleston C, Baoru Y, Tahvonen R, Kallio H, Rimbach GH, Minihane AM. 2002. Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans.:J Nutr Biochem. 13(6):346-354.

 

4. Oxidation  

Chauhan AS, Negi PS, Ramteke RS. 2007. Antioxidant and antibacterial activities of aqueous extract of Seabuckthorn (Hippophae rhamnoides) seeds.:Fitoterapia.  

Chawla R, Arora R, Singh S, Sagar RK, Sharma RK, Kumar R, Sharma A, Gupta ML, Singh S, Prasad J, Khan HA, Swaroop A, Sinha AK, Gupta AK, Tripathi RP, Ahuja PS. 2007. Radioprotective and antioxidant activity of fractionated extracts of berries of Hippophae rhamnoides.:J Med Food. 10(1):101-9.

Jin Yuehua et al. 1989. Super-oxide dismutase from fruit and foliage of common

seabuckthorn (Hippophae rhamnoides L.) Proceedings of International Symposium on Seabuckthorn, Xi'an, China, 350-357.

Rui Livin et a. 1989. Effects of seabuckthorn oil on lipid peroxidation of guinea pigs

erythrocyte membranes. Proceedings of International Symposium on Seabuckthorn, Xi'an, China, 358-364.

Ju Haisong et al. 1989. Scavenging effects of total flavonoids of Hippophae on active

oxygen radicals. Proceedings of International Symposium on Seabuckthorn, Xi'an, China, 365-367.

Yang XY, Qu WJ, Xu ZL, Miu-Qian , Zhu LX, Xu ZM. 2006. Effect of flavonoids from Hippophae rhamniodes residues on blood lipoid metabolism and antioxidative activity in climacteric rats.:Zhongguo Zhong Yao Za Zhi. 31(13):1109-12.  

Suomela JP, Ahotupa M, Yang B, Vasankari T, Kallio H. 2006. Absorption of flavonols derived from sea buckthorn (Hippophae rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans.:J Agric Food Chem. 20;54(19):7364-9.

Shukla SK, Chaudhary P, Kumar IP, Samanta N, Afrin F, Gupta ML, Sharma UK, Sinha AK, Sharma YK, Sharma RK. 2006. Protection from radiation-induced mitochondrial and genomic DNA damage by an extract of Hippophae rhamnoides.:Environ Mol Mutagen. 47(9):647-56.  

Bao M, Lou Y. 2006. Flavonoids from seabuckthorn protect endothelial cells (EA.hy926) from oxidized low-density lipoprotein induced injuries via regulation of LOX-1 and eNOS expression.:J Cardiovasc Pharmacol. 48(1):834-41.

Gupta R, Flora SJ. 2006. Protective effects of fruit extracts of Hippophae rhamnoides L. against arsenic toxicity in Swiss albino mice.:Hum Exp Toxicol. 25(6):285-95.

Liu CL, Liu HQ, Deng YH, Liu ML. 2006. Study on the purification and scavenging free radical activity of water soluble polysaccharide of leave in Hippohae rhamnoides L.:Zhong Yao Cai. 29(2):151-4.  

Goel HC, Gupta D, Gupta S, Garg AP, Bala M. 2005. Protection of mitochondrial system by Hippophae rhamnoides L. against radiation-induced oxidative damage in mice.:J Pharm Pharmacol. 57(1):135-43.

Wu D, Meng Z. 2003. Effect of sulfur dioxide inhalation on the glutathione redox system in mice and protective role of sea buckthorn seed oil.:Arch Environ Contam Toxicol. 45(3):423-8.

Ruan A, Min H, Meng Z, L¨¹ Z. 2003. Protective effects of seabuckthorn seed oil on mouse injury induced by sulfur dioxide inhalation.:Inhal Toxicol. 15(10):1053-8.

Geetha S, Sai Ram M, Mongia SS, Singh V, Ilavazhagan G, Sawhney RC. Evaluation of antioxidant activity of leaf extract of Seabuckthorn (Hippophae rhamnoides L.) on chromium(VI) induced oxidative stress in albino rats.:

Suleyman H, Gumustekin K, Taysi S, Keles S, Oztasan N, Aktas O, Altinkaynak K, Timur H, Akcay F, Akar S, Dane S, Gul M. 2002. Beneficial effects of Hippophae rhamnoides L. on nicotine induced oxidative stress in rat blood compared with vitamin E.:Biol Pharm Bull. 25(9):1133-6.